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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59a522227d3f174710c332a706fb61088fecb48477065c73b9cc12fa3be92191' 
  AND token = 'cs2XYNr9vSZkOC5lnjT6T1gZ7puFDNGMbsrEIop3XTE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}