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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c6bf30b7bde2cc924d87cf10e282788081f9455299194d7ada71e8839272a93' 
  AND token = 'pggFBZj39bM30uNK5UiQm89EquCVimi+XYcUVo204AM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}