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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e054cb0483229e6301df8fad8a00c6f1550c43801a7432c6b2b098c0171c680' 
  AND token = 'dOmxLGwUcvqzSP6PUjFxVTb5JLM4uCRxNV0qLOjD2TU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}