SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bc2a3a4f10e3d09504ff83f8cc14f627e3170930aa8fcb151b84f681473df71' 
  AND token = 'JVst+YC3ox30/8KozJ3wSxHE0eLp3qoK/WhMBsLjrLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}