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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '474e8d8d09dd0219e71e8631d4c677e72acb7641468e19f8f9146b97615d5945' 
  AND token = '+OupWk80aYxD4r4EJ+9HFesrBe7DRZGyxD0+9m6/ujI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}