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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b333d95755b0cef01c20ffea17a85304792e2b51b5ac61688569ddba6696cef' 
  AND token = 'iUL6pxWhs1AJgePO6RmSp2jtn6eu+4VKTwKzq1O12sQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}