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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '605253fa5e0a1459bdffd4cf9708631ccdf7f382a20f5facc4b47cb183fa2d4b' 
  AND token = 'fyDf6mB1lN/gfJ7j4wttnslK2nTxlCnRKjyp/3+PZ0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}