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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53fcd65e2dfc4232eb7fcb9dc669b1415b7e8e92e6f3f9590f80fcda1c361b60' 
  AND token = 'HDpt7EebdstciicB4fXJFGqpT5V36N4P9KUAPiD+PYs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}