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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '527e256e64998b4d21aecca47283a8c62b16364de558394b39ad369e6f4ed4f7' 
  AND token = 'wVnLWDQniRm2rsbLb+irC9ynaJIhdv9TPnyD+Ooraz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}