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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f87ab89e851be91567966a9ccf913e467c7d35b9c3b7ded731886d0229db0d21' 
  AND token = '3mE1uFaoyEIkCUzcIBLmttp+5YPoTDc/5pF81fY8uDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}