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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52e91fc3f63cb0ca63ddb1d2a1db85f4b2d71f3282f3b2cd324860fdcf1545f5' 
  AND token = '4I2CMIlCRvp4cxxqHEpux3AILmkMWQi+RnjN76rsGxk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}