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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cff40083b2ddd64caf7fd0a4dc74644029b0f652b1520bfa95ee488af0d0c7d' 
  AND token = '8z+fwIiXrdtQtgO8PXqFYT6M7znyHWY2PsOftLQLDXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}