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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d19c0b2ab33a73fbb9bf3f86da4f05627caf287efe7680f4cbf8e6208f2ed74' 
  AND token = 'zO2ld4oAxS02iQOZEBR/jsxBqn1bA7OjzHiKWfmexgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}