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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc04725aa24f8e23c14a905bb4ec3bec3234b4fc08c93a90c69d9354d49249a6' 
  AND token = 'u+6jO4sc+RR2yYU2WKFZBTnc44D6i4n3UUKFfljhU5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}