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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '048e79c948c640cc742b524f1ee5db4f15df4727776fe20adf93b5a32da85771' 
  AND token = 'eiMlFswIwKmkJJkVsK5m02XEMfP0iR1GbKsvJ44QkTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}