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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75966a8c3c2b48695fe20fa32ff37628b54a2c777d33855fcfed6fcc038d574c' 
  AND token = 'bIn+nCkdtzL+anCBU4/BrxZ3eQCHgc8nKDGtdWt+3jI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}