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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c42452f62961a3e00255239311be44d2c722cbc549749dc96be79afefed1a22c' 
  AND token = '11gP2AkgA4ocS7rYMvo20I70RgBvIYBQQsg1hn7VLcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}