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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1449a1a0d8bbfdbcdfd6d09f72ccaa1a40efff2cdb9802b46a9df53e707181e2' 
  AND token = '19PZPgKbcm4nuO+8vcJkK2k21B9PUI39Bxs6s1UF9So=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}