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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44cdbaec6a629d7e2b15bf29fa4bcc3c8dca0c7636c379e68c4e6b5d7c602b8a' 
  AND token = 'rTZhJAvOtQ+j1R8wWb11L+to5r7hKAsYdEUqsd5Zrus=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}