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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ae9e1f5ad92a6da4d5f11d6c7e7ad617fbecbe106c3063dea9d14008b3aeb5d' 
  AND token = 'Es9f9GtBhjGv1NXf5ARrwqk+YICpjWFzYcp5SLTe0LM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}