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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '518838a5eb4d0cb6eb784fd3bf4dda69fdb10302aad38b5b32ff65c1e5c00e2b' 
  AND token = 'vUFEQuf/49ilw5BKrhJPfHXFqU5FkSHwTpEtqiULPOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}