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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e4a257960e34f1d340e753e1e1a01a3000511a926b28c1b640b0323e75c17a5' 
  AND token = 'Cm82qp67qmGT1h0YKJKKTmqts6ZuUoMe/pO/9HuJOCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}