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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acf22106e6f9f801042c92a558afe6df05cd29a2ce37786df9c1f2d4412c60da' 
  AND token = 'zBRDngHl1E0T60iW/q37CkV/0g0xMJ8MwAMDuSxxWy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}