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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37941ef89cdad77ede5698d7eb061085b918ba0bdf799e4243c90b3e3dda4ddc' 
  AND token = 'axAGznFeBynyO7Hh+AksehCAC6WZy0GWU/3Nv6fuOwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}