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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f2281c7c22e7d91818f35755d17cfce383edea967bccd75ff14947e8d12070f' 
  AND token = 'db+g6gF6UQNuQgNSPkbs/SSMwJlcNZ8n7XaAU+vDe6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}