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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d969533a1b2ee66ffef13787d5d4d52655425b5616a1ed932e0e57c8435fd07' 
  AND token = 'i1lEVy1Mz+SXDBvuVT9hiOk1tijvMD5QuKWRjQ3qIM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}