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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81e72bb36b3dcc40b0dd0324997e2f5880fa98cd46c1fc9f6a35f7eedfdd2196' 
  AND token = 'f6J1+9OkPs20prR4gy2iBFkfR35aPcFgBTzCaP7wccY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}