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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1abc4d1865b307f70c53effb99ee7cf8b346c05ea36f06e6f0aefae10a78d3ca' 
  AND token = '78gQ2RiWyM30t9hatD65T7epheKP8iQ+/IcvnVD56MU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}