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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11b144b3cb44e593f2b3eaa9289c9919de79daffe08e37a5062716c317d8b870' 
  AND token = '3cE7/JCYK8xFQkjWYNuMra2d063e29XQ+zVUo4oJGBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}