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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1850a627b11bdc8e37ce5de401881644a5b726dc49ddb8628b610f8c976dcd16' 
  AND token = 'it2UjUisiu3gmf7vV/tIpaYKxjIqsbXeBK0je1O3trI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}