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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6222b6f3c7520642be162634b78780194817d1a1bc5ce0ce1b52b9d3e66b552' 
  AND token = '6HX5B9qGZfyHvuu4pKnsM++n+GobAGF41LRBm0vVTP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}