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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '661f980207d379287a5c6ad8b8cf13434203f607f2ed42b63b5b227c23b2143e' 
  AND token = 'e+g0+ytZGq6RUDxPh1VBXT2FW89/i/P2cbakDekQecY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}