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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9248443404033d40f9a8256b3d96130b3b7a720074a1d1b568be8d1af69a3873' 
  AND token = 'q+EvOxBKRdKDcu1GBumaQg0pFR8AAGj0+1aogI+2m5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}