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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7a5c85c5f7229a5def5b61fa00edb2e360c9eeb46c59ef9e853dc4380641c72' 
  AND token = '/TCx0yUwl7wFGNt64L/ykOY3aNtRnpA/82wRJXpNL1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}