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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e75503a587fe90e5110e583835b54d3df0970388be75e90a9888b235335b0d42' 
  AND token = 'ptBmp30PtBw9FBQrS9CLkUpubTF4JVIhkEIbS2fnyCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}