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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4144508484df96ca21754b2f02abacff9e9a293d2992c9e540e61499793f1a06' 
  AND token = '6ZHH5TSzR3ZXLRzprJLi98r7M2t5+2BO/rEmWAfigCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}