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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e9e3fc3c51d1d47b0d0bcf522805039d9dd51be378a5336dbaf0af89603b43c' 
  AND token = 'baNSTE9DBQ+c15lji9SGRoHI+0DAf3FuItOXFksmJDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}