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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7778b74f5e0e6201eece713d4af4dfa85f4a1534f4a8edf1b57b4d03d8290e56' 
  AND token = 'hPSehJIe331eX35VjfdXao9JfbdpeiE03MlMK0kfDk4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}