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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b3ac8a7b613e757594454c7f0a244599fc3bfe6c597c21731edaee1c06825c3' 
  AND token = '42cl+9SLobzNVTM1aQve/R8pCY8FMxsYoBvivDSRmYI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}