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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '223644faa3978071d76b14cd9d4e4fb72e1cb4ac138d4f218451f8f51abd549b' 
  AND token = 'THxR356/SDBtU/CTJCey+laa1/NOTnp3moSEb9GHXCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}