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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea43c143ee0c79ad97eed9bf0530a908f7a36a0fb6b377097874fa8db41191ac' 
  AND token = 'G+mbUB81/FK1p0u+xmj8rxhKTDpLWtc4vnCpaaQ0lNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}