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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6e2bfb04138aecc91fbe5642598af8387157814536cc4704d7e4bfb2e46bb06' 
  AND token = 'efK4bw/8RBiC4MTxH9Oef+KuFZ78WCym1iUpenn74Bc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}