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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f329fd19952ea9ad8aa7a7106f25e0c17a1abf0e13cf7653bec8d7e1c3e0b83' 
  AND token = '22sNsxx+axDs3NLRFVbVioeo4ptOsW/6zIFeNOsWq4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}