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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21604b1827e45c3f726e572a4b44abd0a10953c18359f24f60867c1267b804dc' 
  AND token = 'X25IwycJaNeTCKgQB12JsiWtfZgx700sNgHWERoJ0Jc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}