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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2e7bca09f1bcb9f1a030a8d473a2e188a7d92538a555315b6be56f5a035b6f0' 
  AND token = 'V85/dO+ICK/q6ksVXuW7yVompExQJRCQlERRjqjpdkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}