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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0645dbba3660de63465c3b960ba3b26ab452d18b6f53ee0f838b7d97ace60fa2' 
  AND token = '5C6IKbN6WrmVNi2LVC2JVxPITe1bxqFo1qYKARy5XOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}