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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d50760111a3a5a89cda448783ddcc1972b1e1e2d7a645046402ee31f3693fd2' 
  AND token = 'md7/e+o9zYUDRQ2J5rfSvVQ/y6mBy7p9RJSmHP0L7RU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}