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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78896d90a763bf304ba81c0728eba04960a00aa6de2649cee8b4a484d6370b72' 
  AND token = 'TPdo7b8q3H6dqgHv+gWkbQHrRv3Inx+0VfGvRDIpRIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}