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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4204430df1e4f40e10192f1a77cf666fb77eb92bc4b78d48ebee9edd10f9732a' 
  AND token = 'cXGz19UTzsSGE5NMNFUVMtBej+WY/qhp4o7e/R9OoXQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}