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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aee21d57862ab4586abbf0c2d05e50f24619b8dd351f4c9cafb2c4be4aa384d2' 
  AND token = 'SDxc7v6D/27nS2rPD35IwFjIsv5Dh5aPugr6Hbg9NDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}